St Kilda has made four changes ahead of Friday night's encounter against Brisbane at the Gabba, headlined by debutant Arie Schoenmaker as the red, white and black hunts for a sixth win prior to the bye.

The Tasmanian defender will be joined by the returning Zak Jones, Cooper Sharman and Zaine Cordy; the latter returning to the line-up for the first time since Round 7 against Port Adelaide.

Schoenmaker and Cordy will take the place of the injured Dougal Howard (hamstring) and Jimmy Webster (calf) for Friday's contest, while Nasiah Wanganeen-Milera (managed) and Tim Membrey (omitted) have also made away.

Ryan Byrnes, Ben Paton and Tom Campbell have been named as emergencies.

On the milestones front, Marcus Windhager is set to reach the 50-game mark and will be the first player from the club's Next Generation Academy to do so in Saints colours, while Callum Wilkie will make club history as he equals St Kilda's consecutive games streak (123) to draw level with Jack Newnes and premiership Saint Ian Synman.

St Kilda and Brisbane will go toe-to-toe at the Gabba on Friday 14 June, commencing at 7:40pm AEST.

Round 14

Brisbane v St Kilda
Friday 14 June
Gabba, 7:40pm
Broadcast live on Channel 7, Fox Footy & Kayo

IN: Cordy, Jones, Schoenmaker (debut), Sharman
OUT: Howard (injured), Membrey (omitted), Wanganeen-Milera (managed), Webster (injured)

Last week's substitute: Seb Ross replaced Dougal Howard (hamstring) in the first quarter